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Mir-590 microRNA precursor family : ウィキペディア英語版 | Mir-590 microRNA precursor family In molecular biology mir-590 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. ==Nicotine-induced atrial remodelling== Downregulation of miR-590 by nicotine has been found to play a key part in the generation of atrial fibrosis by atrial structural remodelling. This downregulation sees the removal of post-transcriptional repression of TGF-β1 and TGF-β receptor type II (TGF-βRII), and consequent collagen production.〔 〕 miR-590 downregulation has further been shown to be mediated by activation of alpha-7 nicotinic acetylcholine receptors (α7-nAChRs).
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Mir-590 microRNA precursor family」の詳細全文を読む
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